Symbol MAS1 HUGO 6899 RefSeq NM_002377 | Entrez 4142 OMIM 165180 UniProt P04201 | |
The MAS1 oncogene is a G protein-coupled receptor which binds the angiotensin-II metabolite angiotensin-(1-7). The MAS1 receptor when activated by binding angiotensin-(1-7) opposes many of the effects of angiotensin-II activated angiotensin receptor. Hence MAS1 receptor agonists have similar therapeutic effects as angiotensin-II receptor antagonists including lowering blood pressure.
References
MAS1 oncogene Wikipedia(Text) CC BY-SA