M7GpppN mRNA hydrolase

Updated on Dec 25, 2024

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EC number 3.6.1.62 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

M7GpppN-mRNA hydrolase (EC 3.6.1.62, DCP2, NUDT16, D10 protein, D9 protein, D10 decapping enzyme, decapping enzyme) is an enzyme with systematic name m7GpppN-mRNA m7GDP phosphohydrolase. This enzyme catalyses the following chemical reaction

m7G5'ppp5'-mRNA + H₂O ⇌ m7GDP + 5'-phospho-mRNA

Decapping of mRNA is essential in eukaryotic mRNA turnover.

References

M7GpppN-mRNA hydrolase Wikipedia

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