Trisha Shetty (Editor)

M7GpppN mRNA hydrolase

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EC number
  
3.6.1.62

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

M7GpppN-mRNA hydrolase (EC 3.6.1.62, DCP2, NUDT16, D10 protein, D9 protein, D10 decapping enzyme, decapping enzyme) is an enzyme with systematic name m7GpppN-mRNA m7GDP phosphohydrolase. This enzyme catalyses the following chemical reaction

m7G5'ppp5'-mRNA + H2O ⇌ m7GDP + 5'-phospho-mRNA

Decapping of mRNA is essential in eukaryotic mRNA turnover.

References

M7GpppN-mRNA hydrolase Wikipedia
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