Lyttelton is a surname. Notable people with the surname include:
The Lyttelton family, a British aristocratic family:
Alfred Lyttelton, British politician and sportsman
Arthur Lyttelton, Anglican Bishop
Charles Lyttelton (1714–1768), English churchman and antiquary who served as Bishop of Carlisle 1762–1768 and President of the Society of Antiquaries of London 1765–1768
Charles Lyttelton, 8th Viscount Cobham, British politician and cricketer
Charles Lyttelton, 10th Viscount Cobham, ninth Governor-General of New Zealand and British cricketer
Edward Lyttelton, British sportsman, Schoolmaster and Cleric
George Lyttelton, 1st Baron Lyttelton, British politician
George Lyttelton, 2nd Baron Lyttelton, British politician
George William Lyttelton, 4th Baron Lyttelton, British politician and founder of Canterbury, New Zealand
George William Lyttelton, British teacher and writer
George William Spencer Lyttelton, British civil servant
Humphrey Lyttelton, British jazz musician
John Lyttelton, 9th Viscount Cobham (1881–1949), British politician
John Lyttelton (MP) (died 1601), English politician
John Lyttelton, 11th Viscount Cobham (1943–2006), British nobleman
Sir John Lyttelton (1520–1590), constable of Dudley Castle, England, keeper of parks, Custos Rotulorum of Worcestershire
Oliver Lyttelton, 1st Viscount Chandos, British businessman and politician
Neville Lyttelton, British Army General
Thomas de Littleton, British judge
Thomas Lyttelton, 2nd Baron Lyttelton (1744–1779), British politician
Sarah Lyttelton, Baroness Lyttelton, governess to Edward VII of the United Kingdom and wife of William Lyttelton, 3rd Baron Lyttelton
William Henry Lyttelton, 1st Baron Lyttelton, British colonial governor
William Henry Lyttelton, 3rd Baron Lyttelton, British politician
