Symbol LIPA HUGO 6617 RefSeq NM_000235 | Entrez 3988 OMIM 278000 UniProt P38571 | |
Lysosomal lipase is a form of lipase which functions intracellularly, in the lysosomes.
Clinical significance
A deficiency associated with Lysosomal Acid Lipase Deficiency, Wolman disease, and cholesteryl ester storage disease.
Chlorpromazine is an inhibitor of lysosomal lipase.
A genome wide survey suggests that lysosomal lipase A (located at chromosome 10q23.31) is associated with coronary artery disease in humans.
References
Lysosomal lipase Wikipedia(Text) CC BY-SA