Trisha Shetty (Editor)

Lysine—tRNA(Pyl) ligase

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EC number
  
6.1.1.25

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
782472-12-2

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a lysine-tRNAPyl ligase (EC 6.1.1.25) is an enzyme that catalyzes the chemical reaction

ATP + L-lysine + tRNAPyl ⇌ AMP + diphosphate + L-lysyl-tRNAPyl

The 3 substrates of this enzyme are ATP, L-lysine, and tRNA(Pyl), whereas its 3 products are AMP, diphosphate, and L-lysyl-tRNA(Pyl).

This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-lysine:tRNAPyl ligase (AMP-forming).

References

Lysine—tRNA(Pyl) ligase Wikipedia
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