Lysenko (Ukrainian: Лисенко, Russian: Лысенко) is a Ukrainian surname which may refer to the following people.
Trofim Lysenko (1898–1976), a Soviet agronomist, politician and scientist, after whom the term Lysenkoism was named.
Dmytro Lysenko (born 1981), a Ukrainian diver
Mykola Lysenko (1842–1912), a Ukrainian composer, after whom the Lysenko music school and Lysenko State Conservatory are named.
Sergei Lysenko (footballer, born 1972), a retired Russian football player
Sergei Lysenko (footballer, born 1976), a retired Russian football player
Stanislav Lysenko (born 1972), a retired Russian footballer
Stefan Lysenko, an American actor and Screen Actors Guild member
Tatiana Lysenko (born 1975), a Soviet and Ukrainian gymnast
Tatyana Lysenko (born 1983), a Russian hammer thrower
Viktor Lysenko (1947–2003), a Soviet football player
Vladimir Lysenko (born 1955), a Russian traveller
Volodymyr Lysenko (born 1988), a Ukrainian Association football forward playing for Dynamo Kyiv
Myron Lysenko (1952), an Australian-Ukrainian poet
