Luscombe is a surname. Notable people with the surname include:
Belinda Luscombe, Australian-born journalist
Donald Arthur Luscombe (1895–1965), American businessman and entrepreneur
Francis Luscombe (1849-1926), English rugby union international
Hal Luscombe (born 1981), Wales international rugby union player
John Luscombe (1848-1937), English rugby union international
Lee Luscombe (born 1971), English professional soccer player
Matthew Luscombe (1776–1846), English missionary bishop of the Anglican Communion
Michael Luscombe, Australian businessman - former CEO and Managing Director of Woolworths Limited
Nathan Luscombe (born 1989), English footballer
Stephen Luscombe (born 1954), English musician
Ted Luscombe (born 1924), Anglican bishop and author, Primus of the Scottish Episcopal Church