Lupanine 17 hydroxylase (cytochrome c)

Lupanine 17-hydroxylase (cytochrome c) (EC 1.17.2.2, lupanine dehydrogenase (cytochrome c)) is an enzyme with systematic name lupanine:cytochrome c-oxidoreductase (17-hydroxylating). This enzyme catalyses the following chemical reaction

lupanine + 2 ferricytochrome c + H₂O ⇌ 17-hydroxylupanine + 2 ferrocytochrome c + 2 H⁺

The enzyme isolated from Pseudomonas putida contains heme c and requires pyrroloquinoline quinone (PQQ) for activity