Luciani is an Italian surname. Notable people with the surname include:
Albino Luciani (1912–1978), Italian Pope of the Roman Catholic Church
Alessio Luciani (born 1990), Italian footballer
Anthony Luciani (born 1990), Canadian professional ice hockey player
Dante Luciani (born 1985), Canadian football wide receiver
Giacomo Luciani, Italian expert on the geopolitics of energy
Lucila Luciani de Pérez Díaz (1882–1971), Venezuelan historian, musician and feminist
Luigi Luciani (1842-1919), Italian neuroscientist
Nicoletta Luciani (born 1979), Italian professional volleyball player
Sebastiano Luciani (c. 1485–1547), Italian Renaissance-Mannerist painter, better known as Sebastiano del Piombo
Stefano Luciani (born 1996), Italian individual trampolinist