Lotz is a German surname. Notable people with the surname include:
Anne Graham Lotz (born 1948), American Christian evangelist
Amanda D. Lotz, American educator, Television Scholar, and Media Scholar.
Caity Lotz (born 1986), American actress
Christian Lotz (born 1970), German-American philosopher
Dick Lotz (born 1942), American professional golfer
Gerhard Lotz (born 1936), German engineer
Gernot Lotz (born 1967), German architect
Heinrich Lotz (1905–1982), German engineer
Ingrid Lotz (born 1934), East German athlete who competed mainly in the discus throw event
Irmgard Flügge-Lotz (1903–1974), German mathematician and engineer, the first female engineering professor at the Stanford University
John Lotz (1935-2001), American basketball coach
Károly Lotz (1833–1904), German-Hungarian painter
Kurt Lotz (1912–2005), post-war CEO of the Volkswagen automobile company in Germany
Michael J. Lotz, President and Chief Operating Officer of Mesa Air Group
Wolfgang Lotz (1921–1993), Israeli spy