Lotti may refer to any of the following:
Antonio Lotti (c.1667–1740), Italian composer
Brian Lotti, U.S. professional skateboarder
Carlo Lotti (1916–2013), Italian engineer and professor of hydraulic construction
Carola Lotti (1910–1990), Italian actress
Cosimo Lotti (1571–1643), Italian engineer and landscape designer
Helmut Lotti (born 1969), Belgian singer and songwriter
Marcella Lotti della Santa (1831–1901), Italian opera singer
Mariella Lotti (1921–2006), Italian film actress
Massimo Lotti (born 1969), Italian footballer
Maurizio Lotti (1940–2014), Italian politician
Sahara Lotti (born 1977), U.S. screenwriter and actress
Silvana Di Lotti (born 1942), Italian composer