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Lomefloxacin

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Trade names  Maxaquin
Biological half-life  8 hours
Molar mass  351.348 g/mol
Protein binding  10%
MedlinePlus  a600002
CAS Number  98079-51-7
CAS ID  98079-51-7
Lomefloxacin Lomefloxacin Wikipedia
AHFS/Drugs.com  Consumer Drug Information
ATC code  J01MA07 (WHO) S01AE04 (WHO)

Lomefloxacin hydrochloride (sold under the following brand names in English speaking countries Maxaquin, Okacyn, Uniquin) is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery. Lomefloxacin is associated with phototoxicity and central nervous system adverse effects.

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October 2008 the FDA added the following black box warning to the product insert for Maxaquin: Lomefloxacin is unique in that it forms a magnesium chelate with itself. The chelate is formed between the 2-carbonyl group of two separate lomefloxacin molecules.

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References

Lomefloxacin Wikipedia


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