Trade namesMaxaquin Biological half-life8 hours Molar mass351.348 g/mol Protein binding10%
MedlinePlusa600002 CAS Number98079-51-7 CAS ID98079-51-7
AHFS/Drugs.comConsumer Drug Information ATC codeJ01MA07 (WHO) S01AE04 (WHO)
Lomefloxacin hydrochloride (sold under the following brand names in English speaking countries Maxaquin, Okacyn, Uniquin) is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery. Lomefloxacin is associated with phototoxicity and central nervous system adverse effects.
October 2008 the FDA added the following black box warning to the product insert for Maxaquin: Lomefloxacin is unique in that it forms a magnesium chelate with itself. The chelate is formed between the 2-carbonyl group of two separate lomefloxacin molecules.