Loco or El Loco is a nickname for:
Sebastián Abreu (born 1976), Uruguayan footballer
Willie Alexander (born 1943), American singer and keyboard player
Daniel Barrera Barrera, former Colombian drug lord, arrested 2012
Marcelo Bielsa (born 1955), Argentine football coach
Abdalá Bucaram (born 1952), Ecuadorian politician and President of Ecuador (1996-1997)
René Higuita (born 1966), Colombian retired football goalkeeper
Martín Palermo (born 1973), Argentine retired footballer
Ramón Quiroga (born 1950), Peruvian retired football goalkeeper
Vicente Rodríguez (baseball) (1891-?), Cuban baseball player in the Negro leagues and other leagues
Manuel Valdés (born 1931), Mexican actor and comedian
Juan Manuel Vargas (born 1983), Peruvian footballer
Locó (footballer), Angolan footballer Manuel Armindo Morais Cange (born 1984)
