Rahul Sharma (Editor)

Liver receptor homolog 1

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Species
  
Human

Entrez
  
2494

Human
  
Mouse

Ensembl
  
ENSG00000116833

Liver receptor homolog-1 wwwcellcomcmsattachment20195333942039631417

Aliases
  
NR5A2, B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, LRH1, hB1F-2, nuclear receptor subfamily 5 group A member 2

External IDs
  
OMIM: 604453 MGI: 1346834 HomoloGene: 20827 GeneCards: NR5A2

The liver receptor homolog-1 (LRH-1) also known as NR5A2 (nuclear receptor subfamily 5, group A, member 2) is a protein that in humans is encoded by the NR5A2 gene. LRH-1 is a member of the nuclear receptor family of intracellular transcription factors.

LRH-1 plays a critical role in the regulation of development, cholesterol transport, bile acid homeostasis and steroidogenesis.

LRH-1 is important for maintaining pluripotence of stem cells during embryonic development.

Interactions

Liver receptor homolog-1 has been shown to interact with the small heterodimer partner.

References

Liver receptor homolog-1 Wikipedia
(Text) CC BY-SA


Similar Topics