Species Human Entrez 2494 | Human Mouse Ensembl ENSG00000116833 | |
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Aliases NR5A2, B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, LRH1, hB1F-2, nuclear receptor subfamily 5 group A member 2 External IDs OMIM: 604453 MGI: 1346834 HomoloGene: 20827 GeneCards: NR5A2 | ||
The liver receptor homolog-1 (LRH-1) also known as NR5A2 (nuclear receptor subfamily 5, group A, member 2) is a protein that in humans is encoded by the NR5A2 gene. LRH-1 is a member of the nuclear receptor family of intracellular transcription factors.
LRH-1 plays a critical role in the regulation of development, cholesterol transport, bile acid homeostasis and steroidogenesis.
LRH-1 is important for maintaining pluripotence of stem cells during embryonic development.
Interactions
Liver receptor homolog-1 has been shown to interact with the small heterodimer partner.
References
Liver receptor homolog-1 Wikipedia(Text) CC BY-SA