This is a list of full-block structures in New York City:
111 Eighth Avenue, a full-block Art Deco multi-use building located between Eighth and Ninth Avenues, and 15th and 16th Streets in the Chelsea neighborhood of the Manhattan borough of New York City
731 Lexington Avenue, a 1,400,000 sq ft glass skyscraper on the East Side of Midtown Manhattan, New York City
Alexander Hamilton U.S. Custom House ,built in 1902–07 by the federal government to house the duty collection operations for the Port of New York
American Museum of Natural History, one of the largest museums in the world. The museum complex comprises 27 interconnected buildings housing 45 permanent exhibition halls, in addition to a planetarium and a library
Flatiron Building, a triangular 22-story steel-framed landmarked building located at 175 Fifth Avenue in the borough of Manhattan, New York City
General Theological Seminary, a seminary of the Episcopal Church located between West 20th and 21st Streets and Ninth and Tenth Avenues in the Chelsea neighborhood of Manhattan
Museum of Arts and Design
St. Patrick's Cathedral (Manhattan)
Starrett-Lehigh Building
Trump International Hotel and Tower (New York City)
Tunnel (New York nightclub)
United Palace
Waldorf Astoria New York