EC number 2.4.1.44 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9073-98-7 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a lipopolysaccharide 3-alpha-galactosyltransferase (EC 2.4.1.44) is an enzyme that catalyzes the chemical reaction
UDP-galactose + lipopolysaccharideThus, the two substrates of this enzyme are UDP-galactose and lipopolysaccharide, whereas its two products are UDP and [[3-alpha-D-galactosyl-[lipopolysaccharide glucose]]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase. Other names in common use include UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase, UDP-galactose:polysaccharide galactosyltransferase, uridine diphosphate galactose:lipopolysaccharide, alpha-3-galactosyltransferase, uridine diphosphogalactose-lipopolysaccharide, and alpha,3-galactosyltransferase. This enzyme participates in lipopolysaccharide biosynthesis and glycan structures - biosynthesis 2.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1GA8 and 1SS9.