Samiksha Jaiswal (Editor)

Lipopeptide

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Symbol
  
N/A

OPM superfamily
  
172

TCDB
  
1.D.15

OPM protein
  
1t5n

A lipopeptide is a molecule consisting of a lipid connected to a peptide. Bacteria express these molecules. They are bound by TLR 2, which form a heterodimer with TLR6 or TLR1.
Certain lipopeptides are used as antibiotics. Certain lipopeptides could have strong anifungtal and hemolytic activities. It has been demonstrated that their activity is generally linked to interactions with the plasma membrane and sterol components of plasma membrane could play a major role and can be their privileged partner of interaction.

Examples

  • Surfactin
  • Daptomycin
  • Echinocandins (e.g., caspofungin)
  • iturin A
  • mycosubtilin
  • Bacillomycins
  • References

    Lipopeptide Wikipedia