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Lipoate–protein ligase

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EC number
  
2.7.7.63

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
144114-18-1

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

Lipoate–protein ligase (EC 2.7.7.63, LplA, lipoate protein ligase, lipoate–protein ligase A, LPL, LPL-B) is an enzyme with systematic name ATP:lipoate adenylyltransferase. This enzyme catalyses the following chemical reaction

(1) ATP + lipoate ⇌ diphosphate + lipoyl-AMP (2) lipoyl-AMP + apoprotein ⇌ protein N6-(lipoyl)lysine + AMP

This enzyme requires Mg2+ as a cofactor.

References

Lipoate–protein ligase Wikipedia
(Text) CC BY-SA