Lipoate–protein ligase

Updated on Dec 25, 2024

Edit

Comment

EC number 2.7.7.63 IntEnz IntEnz view ExPASy NiceZyme view		CAS number 144114-18-1 BRENDA BRENDA entry KEGG KEGG entry

Lipoate–protein ligase (EC 2.7.7.63, LplA, lipoate protein ligase, lipoate–protein ligase A, LPL, LPL-B) is an enzyme with systematic name ATP:lipoate adenylyltransferase. This enzyme catalyses the following chemical reaction

(1) ATP + lipoate ⇌ diphosphate + lipoyl-AMP(2) lipoyl-AMP + apoprotein ⇌ protein N⁶-(lipoyl)lysine + AMP

This enzyme requires Mg²⁺ as a cofactor.

References

Lipoate–protein ligase Wikipedia

(Text) CC BY-SA