Limulus clotting factor C

Limulus clotting factor overbar C (EC 3.4.21.84, factor C, limulus factor C) is an enzyme. This enzyme catalyses the following chemical reaction

Selective cleavage of -Arg¹⁰³-Ser- and -Ile¹²⁴-Ile- bonds in limulus clotting factor B to form factor overbar B. Cleavage of -Pro-Arg- bonds in synthetic substrates

This enzyme is isolated from the hemocyte granules of the horseshoe crabs Limulus and Tachypleus.