Lewisohn is a surname. Notable people with the surname include:
Adolph Lewisohn, (1849-1938), German-American merchant and philanthropistLeonard Lewisohn (philanthropist) (1847-1902), German-American merchant and philanthropist, brother of AdolphAlice Lewisohn, (1883-1972), American co-founder of Neighborhood Playhouse and actress, daughter of LeonardIrene Lewisohn (1892-1944), American co-founder of Neighborhood Playhouse and the Museum of Costume Art, daughter of LeonardJesse Lewisohn (1872-1918), American businessman and racehorse owner, son of LeonardLudwig Lewisohn (1882–1955), German-American writerMark Lewisohn (born 1958), British author and historianLeonard Lewisohn (Islamic scholar)