Trade names Livostin Molar mass 420.519 g/mol | Routes ofadministration Ophthalmic, intranasal CAS ID 79516-68-0 | |
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AHFS/Drugs.com Micromedex Detailed Consumer Information Pregnancycategory AU: B3US: C (Risk not ruled out) ATC code R01AC02 (WHO) S01GX02 (WHO) Legal status In general: ℞ (Prescription only) | ||
Levocabastine (trade name Livostin) is a selective second-generation H1 receptor antagonists which was discovered at Janssen Pharmaceutica in 1979. It is used for allergic conjunctivitis.
As well as acting as an antihistamine, levocabastine has also subsequently been found to act as a potent and selective antagonist for the neurotensin receptor NTS2, and was the first drug used to characterise the different neurotensin subtypes. This has made it a useful tool for the study of this receptor.
The pharmaceutical drug Bilina is a combination of Levocabastine, benzalkonium chloride, and other components and is typically used in a 0.5 mg/ml suspension as eye-drops, dispensed in 4ml bottles for the treatment of allergic conjunctivitis or similar allergic ocular conditions.