Lethbridge is a surname. Notable people with the surname include:
Christopher Lethbridge (cricketer) (born 1961), English cricketer
Grace Marguerite Lethbridge or Grace Marguerite Hay Drummond-Hay (1895–1946), the first woman to travel around the world by air
John Lethbridge (1675–1759), inventor of an early diving apparatus in 1715
John Sydney Lethbridge (1897-1961), British soldier
Julian Lethbridge (born 1947), British painter.
Robert Lethbridge, professor of French and Master of Fitzwilliam College Cambridge
Roper Lethbridge (1840–1919), British academic and civil servant in India
Thomas Charles Lethbridge (1901–1971), British explorer, author, archaeologist and psychic researcher
Timothy C. Lethbridge (born 1963), Canadian computer scientists and Professor University of Ottawa
William Lethbridge (1825–1901), after whom the city of Lethbridge, Alberta, was named
Fictional characters:
Brigadier Lethbridge-Stewart, a character on the television show Doctor Who