Lefler is a surname. Notable people with the name include:
Doug Lefler, American film director, screenwriter, film producer and storyboard artist
Franz Lefler (1831–1898), Austrian painter
Heinrich Lefler (1863–1919), Austrian painter, graphic artist and stage designer
John Lefler (born 1975), American songwriter, singer, guitarist, and pianist
Wade Lefler (1896–1981), Major League Baseball player