Ledoux or LeDoux is a surname, and may refer to:
Chris LeDoux (1948–2005), American country music singer-songwriter
Claude Nicolas Ledoux (1736–1806), French architect.
Claude Ledoux (composer) (born 1960), Belgian composer
Gabrielle LeDoux (born 1948), American lawyer and politician
Harold LeDoux (born 1926), American comic artist
Joseph E. LeDoux (born 1949), American neuroscientist
Michel Ledoux (born 1958), French mathematician
Patrice Ledoux, French film producer
Paul Ledoux (1914–1988), Belgian astronomer
Scott LeDoux (1949–2011), American boxer