Large cell neuroendocrine carcinoma of the lung (LCNEC) is a highly malignant neoplasm arising from transformed epithelial cells originating in tissues within the pulmonary tree. It is currently considered to be a subtype of large cell lung carcinoma.
LCNEC is often generically grouped among the non-small cell lung carcinomas.
Variants
The World Health Organization classification of lung tumors recognizes a variant of LCNEC, namely "combined large cell neuroendocrine carcinoma" (c-LCNEC).
References
Large cell neuroendocrine carcinoma of the lung Wikipedia(Text) CC BY-SA