Lajoie is a French surname. Notable people with this surname include:
Bill Lajoie (1934–2010), American baseball player and general manager
Claude Lajoie (born 1928), Canadian Liberal Party member
Corey LaJoie (born 1991), American race car driver, son of Randy LaJoie
Jon Lajoie (born 1980), Canadian comedian, actor, and internet celebrity
Nap Lajoie (1874–1959), American baseball player
Randy LaJoie (born 1961), American race car driver, father of Corey LaJoie
