Entrez 8216 | Ensembl ENSG00000099949 | |
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Aliases LZTR1, BTBD29, LZTR-1, SWNTS2, NS10, leucine-zipper-like transcription regulator 1 External IDs MGI: 1914113 HomoloGene: 4925 GeneCards: LZTR1 | ||
Leucine-zipper-like transcriptional regulator 1 is a protein that in humans is encoded by the LZTR1 gene.
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex.
Clinical significance
Deletion of this gene may be associated with DiGeorge syndrome.
This gene has also been implicated in an autosomal dominant form of schwannomatosis.
References
LZTR1 Wikipedia(Text) CC BY-SA