Aliases LPP Ensembl ENSG00000145012 | Entrez 4026 | |
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External IDs MGI: 2441849 HomoloGene: 4075 GeneCards: LPP |
Function
Lipoma-preferred partner is a subfamily of LIM domain proteins that are characterized by an N-terminal proline rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease related chromosomal translocations which result in the expression of fusion proteins that may promote tumor growth.
References
LPP (gene) Wikipedia(Text) CC BY-SA