Trisha Shetty (Editor)

LPP (gene)

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Aliases
  
LPP

Human
  
Ensembl
  
ENSG00000145012

Species
  
Entrez
  
4026

LPP (gene)

External IDs
  
MGI: 2441849 HomoloGene: 4075 GeneCards: LPP

Lipoma-preferred partner is a protein that in humans is encoded by the LPP gene.

Function

Lipoma-preferred partner is a subfamily of LIM domain proteins that are characterized by an N-terminal proline rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease related chromosomal translocations which result in the expression of fusion proteins that may promote tumor growth.

References

LPP (gene) Wikipedia


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