Species Human Entrez 4004 | Human Mouse Ensembl ENSG00000166407 | |
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Aliases LMO1, RBTN1, RHOM1, TTG1, LIM domain only 1 External IDs MGI: 102812 HomoloGene: 48101 GeneCards: LMO1 | ||
Rhombotin-1 is a protein that in humans is encoded by the LMO1 gene.
LMO1 encodes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted.
Interactions
LMO1 has been shown to interact with GATA3 and TAL1.
References
LMO1 Wikipedia(Text) CC BY-SA