L iditol 2 dehydrogenase

In enzymology, a L-iditol 2-dehydrogenase (EC 1.1.1.14) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are L-iditol and NAD⁺, whereas its 3 products are L-sorbose, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is L-iditol:NAD⁺ 2-oxidoreductase. Other names in common use include polyol dehydrogenase, sorbitol dehydrogenase, L-iditol:NAD⁺ 5-oxidoreductase, L-iditol (sorbitol) dehydrogenase, glucitol dehydrogenase, L-iditol:NAD⁺ oxidoreductase, NAD⁺-dependent sorbitol dehydrogenase, NAD⁺-dependent sorbitol dehydrogenase, and NAD⁺-sorbitol dehydrogenase. This enzyme participates in fructose and mannose metabolism.