Kalpana Kalpana (Editor)

L aspartate oxidase

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
  
1.4.3.16

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
69106-47-4

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a L-aspartate oxidase (EC 1.4.3.16) is an enzyme that catalyzes the chemical reaction

L-aspartate + H2O + O2 oxaloacetate + NH3 + H2O2

The 3 substrates of this enzyme are L-aspartate, H2O, and O2, whereas its 3 products are oxaloacetate, NH3, and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is L-aspartate:oxygen oxidoreductase (deaminating). This enzyme participates in alanine and aspartate metabolism and nicotinate and nicotinamide metabolism. It employs one cofactor, FAD.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1J5P, 1KNP, and 1KNR.

References

L-aspartate oxidase Wikipedia