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Kynurenate 7,8 dihydrodiol dehydrogenase

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EC number
  
1.3.1.18

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37255-30-4

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a kynurenate-7,8-dihydrodiol dehydrogenase (EC 1.3.1.18) is an enzyme that catalyzes the chemical reaction

7,8-dihydro-7,8-dihydroxykynurenate + NAD+ 7,8-dihydroxykynurenate + NADH + H+

Thus, the two substrates of this enzyme are 7,8-dihydro-7,8-dihydroxykynurenate and NAD+, whereas its 3 products are 7,8-dihydroxykynurenate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase. Other names in common use include 7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase, and 7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase. This enzyme participates in tryptophan metabolism.

References

Kynurenate-7,8-dihydrodiol dehydrogenase Wikipedia