Kubo is a Japanese surname. Notable people with the surname include:
Asaka Kubo (born 1979), lead singer of the musical group A+Jyuc
Junko Kubo (born 1972), television announcer in Japan
Ryogo Kubo (1920–1995), Japanese mathematical physicist
Shinji Kubo, a fictional character
Shogo Kubo, member of a group of skateboarders called Z-Boys
Tatsuhiko Kubo (born 1976), Japanese soccer player
Takuro Kubo (born 1971), member of the Japanese rock band GLAY
Tite Kubo (born 1977), Japanese manga artist
Wataru Kubo (1929 – 2003), Japanese politician
Yurika Kubo (born 1989), Japanese voice actress and singer