The surname Kruse may refer to:
Anine Kruse (born 1977), Norwegian music conductor
August von Kruse (1779–1848), German general during the Napoleonic Wars
Frederik Vinding Kruse (1880–1963), Danish jurist
Käthe Kruse (1883–1968), German dollmaker
Max Kruse (author) (1921–2015), German author
Robbie Kruse (born 1988), Australian footballer
Tom Kruse (inventor), inventor of the Hoveround, a type of electric wheelchair
Tom Kruse (mailman) (1914–2011), Australian mailman, featured in documentary The Back of Beyond
Bill Kruse (Australian rules footballer) (1880–1965), Australian footballer
William F. Kruse (1894–1952), American socialist journalist and functionary
The toponym Kruse may refer to:
Kruse, Podgorica, Montenegro