Kretschmer is a German surname. Notable people with the surname include:
Ernst Kretschmer (1888–1964), German psychiatrist
Marian Kretschmer (born 1983), German comics artist
Otto Kretschmer (1912–1998), German U-Boat commander in World War II
Paul Kretschmer (1866–1956), German linguist
Daniel Kretschmer, German hip hop and reggae musician
Tim Kretschmer (1991–2009), German spree killer
Uwe Kretschmer,Highly successful Business Manager