Killer or The Killer is a nickname of:
Pietro Aurino (born 1977), Italian former boxer
Keegan Brown (born 1992), English darts player
Fred Burke (1893-1940), American armed robber and contract killer
Clive Caldwell (1910-1994), Australian World War II flying ace
Doug Gilmour (born 1963), Canadian retired National Hockey League player
Mack Gray (1905-1981), American actor
Derek Hales (born 1951), English former footballer
Kevin Kaminski (born 1969), Canadian former National Hockey League player called "Killer Kaminski"
Arthur Kane (1949-2004), American bass guitarist for the glam rock band the New York Dolls
Harmon Killebrew (1936–2011), American Major League Baseball player
Jerry Lee Lewis (born 1935), American rock-and-roll and country music singer/pianist
Katlego Mphela (born 1984), footballer