Khayat, Khayyat is an Arabic-language occupational surname, literally meaning "tailor". Notable people with the surname include:
Bill Khayat (born 1973), American football coachDavid Khayat (born 1956), French oncologistEd Khayat (born 1935), American football playerJana Khayat, British businesswomanJean Khayat (born 1942), Tunisian Olympic fencerMirna Khayat, Lebanese music video directorNadir Khayat, known by the stage name RedOne, Morocco-born Swedish producer and songwriterRobert Khayat (born 1938), American academic, Chancellor of the University of MississippiElías Khayat (born 1939 in Syria, Naturalized Argentinean), Violinist, Musical Director, Director of 'Camerata Bariloche' 1980-1992 chamber orchestra