Khalaf is both a given name and a surname. Notable people with the name include:
Given name:
Khalaf al-Bazzar (d. 844), canonical reader of the Qur'anKhalaf I (937–1009), Amir of SistanKhalaf Al-Enezi (born 1952), Kuwaiti politicianKhalaf Al Salamah (born 1979), Kuwaiti footballerKhalaf al-Ulayyan, Iraqi politicianKhalaf Khalafov (born 1959), Azerbaijani politicianKhalaf Masa'deh (died 2015), Jordanian lawyer and politicianKhalaf M Alanazi, Faculty member at Northern Border University, Saudi ArabiaSurname:
Abbas Khalaf, Iraqi translatorAbdulhadi Khalaf (born 1945), Bahrani political activist and academicAbdulhadi Khalaf (footballer) (born 1986), Syrian footballerAhmad Ibrahim Khalaf (born 1992), Iraqi footballerAline Khalaf (born 1974), Lebanese singerKarim Khalaf (1935–1985), Palestinian politicianKhaled Khalaf (born 1983), Kuwaiti footballerMohamed Khalaf, Egyptian footballerRima Khalaf (born 1953), Jordanian UN officialSalah Khalaf (1933–1991), Palestinian PLO officialSamir Khalaf (born 1933), Lebanese sociologistUbay ibn Khalaf, contemporary of MuhammadUmayyah ibn Khalaf, contemporary of Muhammad