Karlheinz is a German given name, composed of Karl and Heinz. Notable people with that name include:
Karlheinz Böhm (1928–2014), Austrian actor
Karlheinz Brandenburg (born 1954), audio engineer
Karlheinz Deschner (born 1924), German agnostic
Karlheinz Essl (born 1960), Austrian composer, performer, sound artist, improviser and composition teacher
Karlheinz Förster (born 1958), former German football player
Karlheinz Hackl (born 1949), Austrian actor
Karlheinz Kaske (1928–1998), German manager and CEO of the Siemens AG
Karlheinz Klotz (born 1950), West German athlete
Karlheinz Martin (1886–1948), German stage and film director
Karlheinz Oswald (born 1958), German sculptor
Karlheinz Pflipsen (born 1970), retired German soccer player
Karlheinz Schreiber (born 1934), German-born lobbyist, fundraiser, arms dealer and businessman
Karlheinz Stockhausen (1928–2007), German composer
Karlheinz Zöller (1928–2005), German flutist