Karlapat Wildlife Sanctuary (Odia: କର୍ଲାପାଟ୍;Hindi: कर्लापाट्) is a wildlife sanctuary located in Kalahandi district and a very popular tourist attraction of Odisha in India. Karlapat Wildlife Sanctuary is about 15 km from Bhawanipatna, the district headquarters of Kalahandi district.
The sanctuary covers an area of 175 square kilometres (68 sq mi). It lies within the Eastern Highlands moist deciduous forests ecoregion. Major plant communities include mixed deciduous forests and scrublands.
This sanctuary is home to many wildlife species like tiger, leopard, sambar, nilgai, barking deer, mouse deer, a wide variety of birds like green munia, Great Eared-nightjar and various reptiles.