Samiksha Jaiswal (Editor)

KDM5C

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Species
  
Entrez
  
8242

Human
  
Ensembl
  
ENSG00000126012

KDM5C

Aliases
  
KDM5C, DXS1272E, JARID1C, MRX13, MRXJ, MRXSCJ, MRXSJ, SMCX, XE169, lysine demethylase 5C

External IDs
  
MGI: 99781 HomoloGene: 79498 GeneCards: KDM5C

Lysine-specific demethylase 5C is an enzyme that in humans is encoded by the KDM5C gene.

Function

This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.

References

KDM5C Wikipedia


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