Species Human Entrez 3760 | Human Mouse Ensembl ENSG00000162989 | |
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Aliases KCNJ3, GIRK1, KGA, KIR3.1, potassium voltage-gated channel subfamily J member 3 External IDs MGI: 104742 HomoloGene: 1687 GeneCards: KCNJ3 |
Potassium inwardly-rectifying channel, subfamily J, member 3, also known as KCNJ3 or Kir3.1, is a human gene.
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a hetero-tetrameric pore-forming complex.
Interactions
KCNJ3 has been shown to interact with KCNJ5.
References
KCNJ3 Wikipedia(Text) CC BY-SA