Species Human Entrez 30819 | Human Mouse Ensembl ENSG00000120049 | |
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Aliases KCNIP2, KCHIP2, potassium voltage-gated channel interacting protein 2 External IDs MGI: 2135916 HomoloGene: 23710 GeneCards: KCNIP2 | ||
Kv channel-interacting protein 2 also known as KChIP2 is a protein that in humans is encoded by the KCNIP2 gene.
Function
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs, also frequently called "KChIP"), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Alternative splicing results in multiple transcript variant encoding different isoforms.
References
KCNIP2 Wikipedia(Text) CC BY-SA