Entrez 10300 | Ensembl ENSG00000140854 | |
![]() | ||
Aliases KATNB1, KAT, LIS6, katanin regulatory subunit B1 External IDs MGI: 1921437 HomoloGene: 4302 GeneCards: KATNB1 |
Katanin p80 WD40-containing subunit B1 is a protein that in humans is encoded by the KATNB1 gene.
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases.
References
KATNB1 Wikipedia(Text) CC BY-SA