Samiksha Jaiswal (Editor)

KATNA1

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Aliases
  
KATNA1

Human
  
Ensembl
  
ENSG00000186625

Species
  
Entrez
  
11104

External IDs
  
MGI: 1344353 HomoloGene: 56014 GeneCards: KATNA1

Katanin p60 ATPase-containing subunit A1 is an enzyme that in humans is encoded by the KATNA1 gene.

Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases.

References

KATNA1 Wikipedia


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