Kārlis or Karlis may refer to:
Kārlis Aperāts (1892–1944), Standartenführer in the Waffen SS during World War II
Kārlis Balodis (1864–1931), Latvian economist, financist, statistician and demographist
Kārlis Bētiņš (1867–1943), Latvian chess master and composer of studies
Kārlis Baumanis (1835–1905), better known as Baumaņu Kārlis, a Latvian composer
Karlis Ezergailis, Australian Motorcycle speedway rider
Kārlis Goppers (1876–1941), Latvian military officer and the founder and President of Latvijas Skautu un Gaidu Centrālā Organizācija
Hugo Kārlis Grotuss (1884–1951), Latvian painter, classified as a Realist
Kārlis Irbītis (1904–1997), Latvian aeroplane designer
Kārlis Lācis (born 1977), Latvian composer
Kārlis Leiškalns (born 1951), Latvian politician
Kārlis Lejnieks (born 1988), retired Latvian tennis player currently pursuing interest in coaching
Kārlis Kepke (1890-????), Latvian cyclist and Olympic competitor
Kārlis Klāsens (????-????), Latvian sailor and Olympic competitor
Kārlis Klāsups (1922-1991), Latvian chess master
Kārlis Kļava (1907–1941), Latvian sports shooter and Olympic competitor
Kārlis Lobe (1895–1985), Latvian Nazi collaborator and high-ranking Waffen-SS officer
Kārlis Mīlenbahs (1853–1916), the first native speaker of Latvian to devote his career to linguistics
Kārlis Mūsiņš (1919–1955), Latvian Untersturmführer in the Waffen-SS during WWII
Kārlis Muižnieks (born 1964), former basketball player, head coach of Barons LMT
Karlis Osis (1917–1997), Latvian-born American parapsychologist
Karlis Ozols (1912–2001), Latvian-Australian chess player
Kārlis Padegs (1911–1940), Latvian artist
Kārlis Prauls (1895–1941), Latvian general, from 1930 to 1940 was a commander of Aizsargi organization
Kārlis Sensbergs, Waffen-Unterscharführer in the Waffen SS during World War II
Kārlis Skalbe (1879–1945), Latvian writer, poet, and activist
Kārlis Skrastiņš (born 1974), Latvian professional ice hockey defenceman
Kārlis Smilga (born 1975), Latvian curler from Jelgava
Kārlis Šteins (1911–1983), Latvian and Soviet astronomer
Kārlis Tīls (1906-196?), Latvian international football defender and football manager
Kārlis Ulmanis (1877–1942), prominent Latvian politician in pre-World War II Latvia
Kārlis Vilciņš (1892–1972), Latvian wrestler and Olympic competitor
Kārlis Zāle (1888–1942), Latvian sculptor
Kārlis Zariņš (1879—1963), Latvian diplomat
Kārlis Zariņš (1889–1978), Latvian writer
Kārlis Zirnis (born 1977), Latvian hockey player
