José Luis Serna Alzate

José Luis Serna Alzate (February 17, 1936 – September 28, 2014) was a Roman Catholic bishop.

Ordained to the priesthood for the Consolata Missionaries, Serna Alzate was named Vicar Apostolic of Florencia, Colombia, in 1978. In 1985, he was named the first bishop of the Roman Catholic Diocese of Florencia and then was named bishop of the newly-established Roman Catholic Diocese of Libano–Honda in 1989. He resigned in 2002.