Jobe is both a surname and a given name. Notable people with the name include:
Surname:
Ann Wynia, née Jobe (born 1943), former member of the Minnesota House of Representatives
Ben Jobe, American former men's college basketball head coach
Brandt Jobe (born 1965), American golfer
Frank Jobe, American orthopedic surgeon who performed the first "Tommy John surgery"
Georges Jobé (born 1961), five-time FIM motocross world champion from Belgium
Kari Jobe (born 1981), American Christian singer and songwriter
Maba Jobe (born 1965?), Gambian army officer and politician
Momodou Lamin Sedat Jobe (born 1944), Foreign Minister of Gambia from 1998 to 2001
Sami Jo (born Jane Annette Jobe in 1947), American country singer
Given name:
JoBe Cerny, voice and character actor, producer and director, best known as the voice of the Pillsbury Doughboy
Jobe Watson (born 1985), Australian rules footballer
Jobe Wheelhouse (born 1985), Australian footballer