Tripti Joshi (Editor)

Joachim Boldt

Updated on
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Name  Joachim Boldt

Books  Hemodynamic Monitoring
Joachim Boldt wwwrettungsdienstdenewswpcontentuploads2009

Similar People  Yoshitaka Fujii, Scott Reuben, Steven Shafer


Joachim Boldt (born September 29, 1954) is a German anesthesiologist who was previously considered a leading researcher into colloids. He has been stripped of his professorship and is under criminal investigation for possible forgery of up to 90 research studies.

Joachim Boldt joachim boldt retractions Archives Retraction Watch at Retraction

The editors of 16 different scientific journals, including Anesthesia & Analgesia, Anaesthesia, the European Journal of Anaesthesiology and the British Journal of Anaesthesia, allege that 89 of 102 studies published by Boldt contained research without proper institutional review board approval.

On November 10, 2010, Boldt was suspended from Klinikum Ludwigshafen, a hospital in Germany, for a scientific publication in Anesthesia & Analgesia with insufficient background research. His field of research and the publications were related to hydroxyethyl starch (HES). Some 90 studies he published are currently being reviewed by medical authorities.

In February 2011, Boldt was stripped of his title of professor at the University of Giessen for failing to teach, and the university is investigating possible charges of scientific misconduct. His case was described at the time as "possibly the biggest medical research scandal since Andrew Wakefield was struck off in 2010 for falsely claiming to have proved a link between the MMR vaccine and autism".

In August 2012, the hospital released the results of its investigation: while no patients were harmed, "in a large number of the studies investigated, the conduct of research failed to meet required standards. False data were published in at least 10 of the 91 articles examined, including, for instance, data on patient numbers/ study groups as well as data on the timing of measurements".

On February 20, 2013, JAMA published a metaanalysis on HES in critically ill patients (Zachyranski R et al.) Boldt had 7 studies from the 1990s that had not yet been retracted. Including them, there was no increase in mortality, but excluding them, there was a significant increase in mortality. Only the Boldt studies showed an improvement with HES; all other studies showed the opposite. It is believed that his fraudulent studies put critically ill patients at risk and caused harm.

An overview of the challenges for meta-analysts presented by the fraud has recently been published. It includes double publication of studies, manipulating demographic and outcome data to conceal double publication and getting better results for a drug being tested.


The Watchtower's Medical Expert - Health - Nigeria
Joachim Boldt Wikipedia