Jeffries /ˈdʒɛfriz/ is a surname. Notable people with the surname include:
Adam Jeffries (b. 1976), American actor
Ben Jeffries (b. 1980), Australian rugby league footballer
Bill Jeffries (b. 1945), former New Zealand politician
Chris Jeffries (b. 1978), Canadian cross-country skier
Clarence Smith Jeffries (1894–1917), Australian Victoria Cross recipient
Darren Jeffries (b. 1982), British actor
Dean Jeffries (1993–2013), American stunt performer and coordinator
Derek Jeffries (b. 1951), English former footballer
Donald Jeffries (b. 1956), American writer
Doug Jeffries (b. 1966), American writer, director and pornographic actor
Edward Jeffries (1900–1950), Mayor of Detroit, Michigan (1940–48)
Fran Jeffries (b. 1937), American singer, actress and model
Greg Jeffries (American football) (b. 1971), former American footballer
Hakeem Jeffries (b. 1970), American politician
Herb Jeffries (1913–2014), American jazz singer
James Jeffries (disambiguation), several people, including:
James Jeffries (Louisiana), Louisiana Lt. Governor
James Edmund Jeffries (1925–1997), Kansas congressman
James J. Jeffries (1875–1953), boxing champion
Jim Jeffries (comedian) (born 1977), Australian comedian
Jim Jeffries (baseball) (1893–1938), American Negro league baseball player
Jared Jeffries (b. 1981), American basketball player
John Calvin Jeffries (b. c.1948), American law professor
John Jeffries (1744–1819), Boston physician
Kevin Jeffries (b. 1964), American politician
Lang Jeffries (1930–1987), Canadian-American actor
Leonard Jeffries (b. 1937), American professor of Black Studies
Lionel Jeffries (1926–2010), English actor
Maud Jeffries (1869–1946), American actress who married and settled in Australia
Mary Jeffries (1854–1907), London brothel madam
Mike Jeffries (soccer) (b. 1962), retired American soccer player
Mike Jeffries (CEO) (b. 1944), American CEO
Philip M. Jeffries (1925–1987), American set decorator
Rich Jeffries (1938–2012), American former television announcer
Ron Jeffries (b. 1939), American computer scientist
Rosemary Jeffries, American nun and educator
Sabrina Jeffries, American author
Ted Jeffries (1908–1985), American football coach
Thomas Jeffries (died 1826), Australian outlaw & prisoner
Tony Jeffries (b. 1985), English professional boxer
Walter S. Jeffries (1893–1954), American politician
Walter V. Jeffries (b. 1962), American farmer, business man, author and inventor
Willie Jeffries (b. 1937), American college football coach
